The purpose of this study is to determine which method of providing parenteral nutrition (complete intravenous nutrition) will provide the best nutritional and clinical results to children undergoing hematopoietic stem cell transplantation.
Study Type
INTERVENTIONAL
Allocation
RANDOMIZED
Purpose
TREATMENT
Masking
QUADRUPLE
Enrollment
26
Changes in % body fat at baseline, day +30, and day +100.
Time frame: day 30
Body composition measured by DXA, BIA, and 4-site skinfolds.
Time frame: baseline, day 30, and day 100
Changes in body composition from baseline to day +100.
Time frame: day 100
Insulin resistance, defined by HOMA, at each time point.
Time frame: baseline, day 30, and day 100
Measured resting energy expenditure (REE) at each time point.
Time frame: baseline, day 30, and day 100
Changes in percent predicted REE between the two groups.
Time frame: baseline, day 30, and day 100
Correlation between body composition and measured REE.
Time frame: baseline, day 30, and day 100
Resumption of oral intake.
Time frame: day 30
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