RESTOR-MV: Randomized Evaluation of a Surgical Treatment for Off-Pump Repair of the Mitral Valve

Inclusion Criteria: * Grade 2, 3, or 4 functional mitral valve regurgitation per 2D echocardiography * Patient undergoing concomitant coronary artery bypass graft surgery, either on-pump or off-pump * Left ventricular ejection fraction greater than or equal to 25% * Age between 18 and 80 years, inclusive * Patient is willing and available to return for study follow up * Ability of the patient or legal representative to understand and provide signed consent for participating in the study. Exclusion Criteria: * Structural abnormality of the mitral valve (e.g. calcification or thickening of the valve leaflets, ruptured papillary muscle, ruptured chordae tendinae, mitral valve prolapse, mitral stenosis, etc.) * Asymptomatic Grade 2 MR (those with NYHA Class \< II AND LVEF \> 40%) * Organic valve disease resulting in insufficiency or stenosis of the aortic, pulmonary or tricuspid valve requiring surgical intervention * Transmural myocardial infarction within 30 day period prior to surgical placement of Coapsys * NYHA class IV * Left ventricular end diastolic diameter \> 7.0 cm * Cardiac surgery on an emergency or salvage basis * Left atrial or left ventricular thrombus * Left ventricular aneurysm * Previous mitral valve surgery or other previous cardiac surgery that would preclude proper placement of the Coapsys * Chronic renal failure requiring dialysis * Open chest surgery contraindication (e.g., acute respiratory distress, endocarditis, myocarditis, pericarditis) * Active infection * Life expectancy of less than 24 months due to conditions other than their cardiac status * Participation in another investigational drug or device protocol * Abnormal coronary or cardiac anatomy such that the device could not be placed without interfering with those anatomical structures.