4% Intrauterine Lidocaine Infusion for Pain Management in First Trimester Abortions

Oregon Health and Science University80 enrolled

Overview

Recent studies have investigated the use of local anesthetics (i.e. lidocaine, mepivacaine) to lessen the pain experienced with minor gynecologic procedures such as endometrial biopsy and office hysteroscopy. Local anesthetic injected into the uterine cavity has been demonstrated effective in some studies at decreasing patient pain associated with these intrauterine procedures at an anesthetic concentration of at least 2%. Based on this evidence, we hypothesized that an intrauterine lidocaine infusion may reduce patient pain during first trimester abortions.

Study Type

INTERVENTIONAL

Allocation

RANDOMIZED

Purpose

TREATMENT

Masking

DOUBLE

Enrollment

Conditions

Pain

Interventions

Intrauterine lidocaine infusion 4%DRUG

Eligibility

Sex: FEMALEMin age: 18 YearsHealthy volunteers:

Medical Language ↔ Plain English

Inclusion Criteria: * Age \> 18 years old * Good general health * English speaking * Confirmation of gestational age by ultrasound * Body weight \> 100 lbs. * Pregnancy \< 11 weeks

Locations (1)

Planned Parenthood of the Columbia Willamette

Portland, Oregon, United States

Outcomes

Primary Outcomes

VAS scores during cervical dilation and uterine aspiration

Secondary Outcomes

Patient satisfaction, symptoms, lidocaine levels

Data from ClinicalTrials.gov

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