Study of Peri-Operative Docetaxel Plus Laparoscopic Radical Prostatectomy in Prostate Cancer Patients

Inclusion Criteria: * Patients older than 18 years and less than 70 years * Histologically-proven Gleason 7 adenocarcinoma of the prostate * pT2a or pT2b disease based on biopsies of the prostate * More than 2/3 of positive biopsies or 15 ≤ serum PSA \<20 * No previous carcinoma, except basal-cell carcinoma of the skin * Adequate renal function: measured or calculated creatinine clearance\> 60 ml/min * Absolute granulocyte count ≥ 1,500/mm3, platelets ≥ 100,000 mm3, bilirubin ≤ 1.5 fold the upper normal value * Signed informed consent. Exclusion Criteria: * Patients infected by the Human Immunodeficiency Virus (HIV) * Contra-indication to general anesthesia or surgery * Patients who do not fit inclusion criteria