Study Evaluating Combination of Levonorgestrel (LNG) and Ethinyl Estradiol (EE) in Premenstrual Dysphoric Disorder

Inclusion Criteria: * Generally healthy, women aged 18 to 49 years. * History of severe PMS symptoms over the last year, as determined by the investigator. * Regular 21 to 35 day menstrual cycle for 2 months prior to first study visit. Exclusion Criteria: * Major depressive disorder requiring antidepressant treatment or hospitalization within the last 3 years. * Contraindication to combination oral contraceptives. * Use of antidepressants/anxiolytics within 10 days of screening and for the duration of the study. Other exclusions apply.