Study of Transdermal Testosterone Patches in Menopausal Women With Low Libido

Inclusion Criteria: * Be a generally healthy surgically menopausal woman (12 months), 20 to 70 years of age, not receiving any systemic estrogen or estrogen progestin therapy * Be a generally healthy naturally menopausal woman (2 years since last period), 40 to 70 years of age, not receiving any systemic estrogen or estrogen progestin therapy. * Be, in their own judgment, in a stable monogamous sexual relationship for at least one year prior to study entry that is perceived to be secure and communicative with the same partner who is sexually functional and physically present at least 50% of the time. * Answer affirmatively to ALL of the following questions: 1. Was the patient's sex life before menopause good and satisfying in general? 2. Since menopause, has a meaningful loss in the level of desire for sex occurred? 3. Since menopause, has a significant decrease in sexual activity occurred? 4. Is the current level of desire for or interest in sex bothering or concerning? 5. Is an increase in the level of interest in or desire for sex and sexual activity desired? Exclusion Criteria: * Physical limitations that would interfere with normal sexual function; * Estrogen use in the last 12 weeks (vaginal estriol or low dose vaginal estradiol accepted) * Use of any of the following medications: * antiandrogen therapy or topical minoxidil (last 5 years), * androgen therapy (past 3 months/implantable past 7 months), * systemic corticosteroids, * selective serotonin reuptake inhibitors (SSRIs), * tricyclic anti-depressants, * anti-androgens, * systemic beta-blockers, * anti-adrenergics, * spironolactone, * apomorphine, * phosphodiesterase type 5 (PDE5) inhibitors (e.g., Viagra, tibolone or selective estrogen receptor modulators (SERMs), including tamoxifen (last 12 weeks)) * Be experiencing any chronic or acute life stress relating to any major life change that may significantly interfere with sexual function; * Have significant psychiatric disorder (including mild depressive disorder - Beck Depression Inventory-II score of \> 14; * Have current severe dermatological problems or a known suspected hypersensitivity or allergy to any adhesive or any of the constituents of the transdermal testosterone patch * Have evidence of or history of malignancy (estrogen dependent or any gynecological cancer) within the last 5 years; * Have diabetes mellitus, active gallbladder disease, unstable thyroid disease, history of cerebrovascular disease, thrombo-embolic disorders, myocardial infarction or angina within the last 5 years or other significant organic disease that would prevent the patient from completing the study, or otherwise affect the outcome of the study. * Have significant abnormal pretreatment laboratory parameters.