The purpose of this study is to examine whether vitamin D treatment is effective in Crohn's disease.
Crohns Disease is an inflammatory disease of primarily the small intestine and colon. In recent years scientists have hypothesized that low blood vitamin-D levels play a role in the development of autoimmune diseases, including Crohns disease. The purpose of this study is to examine whether vitamin-D is effective in keeping remission in inactive Crohns Disease (double blind placebo controlled trial). The patients who have active disease in the placebo group (reach primary endpoint), will in an open setting receive a higher single dose vitamin-D and the effect will be measured within 4 weeks.
Study Type
INTERVENTIONAL
Allocation
RANDOMIZED
Purpose
TREATMENT
Masking
DOUBLE
Enrollment
110
Aarhus University Hospital, Department V
Aarhus, Denmark
Hospital of Horsens
Horsens, Denmark
Hospital of Randers
Randers, Denmark
Hospital of Silkeborg
Silkeborg, Denmark
Relapse rate within 1 year treatment; CDAI>220
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