The purposes of this study are: * to determine if bilateral pallidal deep brain stimulation results in improvement in neck postures/movements; * to determine if bilateral pallidal deep brain stimulation results in improvement in quality of life; and * to document the adverse effects of surgery in patients with cervical dystonia.
Deep brain stimulation (DBS) of the globus pallidus has been proposed as a treatment for cervical dystonia. At present there are only anecdotal reports of benefit. The objective of this project is to prospectively assess the outcomes of DBS on cervical dystonia in a blinded manner. Our hypothesis is that in patients refractory to medical management, bilateral pallidal DBS will reduce the severity of cervical dystonia at 1 year follow up. The research plan is that of a feasibility study, examining outcomes of 10 patients who would be referred for surgical management due to the severity of their disease. The Toronto Western Spasmodic Torticollis Rating Scale (TWSTR) will be preformed by a blinded neurologist at the completion of the trial.
Study Type
INTERVENTIONAL
Allocation
NON_RANDOMIZED
Purpose
TREATMENT
Masking
SINGLE
Enrollment
10
Dr. Zelma Kiss
Calgary, Alberta, Canada
Dr. Matt Wheatley
Edmonton, Alberta, Canada
Dr. Chris Honey
Vancouver, British Columbia, Canada
Dr. Jerry Krcek
Winnipeg, Manitoba, Canada
Dr. Andrew Parrent
Improvement in neck postures/movements
Improvement in quality of life
Document adverse effects of surgery
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London, Ontario, Canada