Effect of HIV Protease Inhibitor Drugs on Glucose and Insulin Metabolism

Bristol-Myers Squibb25 enrolled

Overview

This study examined the effects of two commonly prescribed HIV drugs on the way the body metabolizes glucose, insulin and fat.

Study Type

INTERVENTIONAL

Allocation

RANDOMIZED

Purpose

TREATMENT

Masking

NONE

Enrollment

Sex: ALLMin age: 18 YearsMax age: 65 YearsHealthy volunteers:

Medical Language ↔ Plain English

Inclusion Criteria: * Healthy volunteers

Clinical Pharmacology Unit, Bristol-Myers Squibb Company

Hamilton, New Jersey, United States

Insulin sensitivity by euglycemic hyperinsulinemic clamp method

Insulin sensitivity by oral glucose tolerance

Lipids and lipoproteins

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