The researchers tested the hypothesis that a protein pulse-feeding pattern was more efficient in improving muscle mass and immune functions than was a protein spread-feeding pattern, after 45 days, in elderly malnourished patients.
To estimate the amelioration of the accretion in protein and the immunizing deficit thanks to a nutrition "PULSEE" ( to hold on 80 % of the proteic by day in on meal) with a proteic distributed all along the day for old subjects having a denutrition To also estimate that the diminution of the morbidity decrease (infections, bedsores) the average during the stay and the mortality according to 2 modalities of grip nutritional
Study Type
INTERVENTIONAL
Allocation
RANDOMIZED
Purpose
TREATMENT
Masking
NONE
Enrollment
68
Dietary protein (80% of daily intake) was consumed in one meal (12.00h)
Dietary protein was spread over the four meals.
Hôpital Emile-Roux (AP-HP)
Limeil-Brévannes, France
Lean mass (dual energy X-ray absorptiometry [DEXA] and bioelectrical-impedance analysis [BIA])
Time frame: 42 days
Immune functions
Time frame: 42 days
Hand-grip strength
Time frame: 42 days
Biological nutritional parameters
Time frame: 42 days
Mortality and morbidity (infections and bedsores)
Time frame: 42 days
Activity of Daily Living (ADL)
Time frame: 42 days
Plasmatic amino acid levels
Time frame: 42 days
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