The main aim of the study is to investigate whether taking Tolterodine for overactive bladder symptoms can reduce the thickness of the bladder wall, as measured by intra-vaginal ultrasound. This will help doctors to understand whether there is a link between changes in the thickness of the bladder wall and progression of symptoms.
Study Type
INTERVENTIONAL
Allocation
RANDOMIZED
Purpose
TREATMENT
Masking
DOUBLE
Enrollment
80
Pfizer Investigational Site
Blackburn, Lancashire, United Kingdom
Pfizer Investigational Site
Harrow, Middx, United Kingdom
Pfizer Investigational Site
Oxford, Oxfordshire, United Kingdom
The main outcome will be the change in bladder wall thickness, as measured by intra-vaginal ultrasound from baseline to week 12.
Secondary outcomes are the change in bladder wall thickness, as measured by intra-vaginal ultrasound from baseline to week 24
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Pfizer Investigational Site
Livingston, West Lothian, United Kingdom
Pfizer Investigational Site
Basingstoke, United Kingdom
Pfizer Investigational Site
Birmingham, United Kingdom
Pfizer Investigational Site
Cambs, United Kingdom
Pfizer Investigational Site
London, United Kingdom
Pfizer Investigational Site
London, United Kingdom
Pfizer Investigational Site
Northampton, United Kingdom
...and 1 more locations