Beta-CIT-SPECT and Neurophysiology in Depression

Ludwig-Maximilians - University of Munich30 enrolled

Overview

Aim of this project is to investigate the effects of escitalopram on monoamine transporter (SERT, DAT) availabilities as assessed by b-CIT and SPECT, and on neurophysiological parameters such as the loudness dependence of auditory evoked potentials (LDAEP) in patients with depression.

Study Type

INTERVENTIONAL

Allocation

NON_RANDOMIZED

Purpose

DIAGNOSTIC

Masking

NONE

Enrollment

Conditions

Depression

Interventions

β-CIT-SPECT, NeurophysiologyPROCEDURE

β-CIT-SPECT scans and EEG recordings, two assessments each

Eligibility

Sex: ALLMin age: 18 Years

Medical Language ↔ Plain English

Inclusion Criteria: * Psychiatric in or outpatients with acute depressive episode * Indication for pharmacological treatment Exclusion Criteria: * Acute suicidality * Neurological or severe somatic disorders * Occupational exposition to radiation \>15 mSv per year * Women during pregnancy or lactation

Locations (1)

Depts. of Psychiatry and Nuclear Medicine, Ludwig-Maximilians-University of Munich

Munich, Germany

Outcomes

Primary Outcomes

changes in β-CIT/neurophysiological measurements from baseline to week 4

Time frame: two assessments, at baseline and week 4

Data from ClinicalTrials.gov

This platform is for informational purposes only and does not constitute medical advice. Always consult a qualified healthcare professional.