Osteopenia and osteoporosis are increasingly reported in HIV-infected patients, and appear to be more frequent than in general population. However, pathogenesis remains unclear, and published studies still give non concordant results. We therefore started a prospective study, to assess the potential role of ARV in the occurrence of osteopenia and osteoporosis. BMD evolution over a 2-years period of follow-up, will be compared between patients starting ARV therapy, and subjects without HAART (no indication of treatment). A correlation between BMD and several factors will be looked at (see below). This study with individual direct benefice, is conducted in 3 outpatients clinics (Strasbourg, Colmar, Mulhouse) in collaboration with the rheumatologic teams. 60 patients are planned to be included over a 3-years inclusion period
Study Type
INTERVENTIONAL
Allocation
NON_RANDOMIZED
Purpose
BASIC_SCIENCE
Masking
NONE
Enrollment
44
Treated with antiretrovirals
Centre Hospitalier de Colmar
Colmar, France
Centre Hospitalier de Mulhouse
Mulhouse, France
Hôpitaux Universitaires de Strasbourg
Strasbourg, France
BMD evolution and modification during 2 years of follow-up, compared between treated and untreated subjects
Time frame: From enrollment to the end of follow-up at 2 years
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