A Trial to Evaluate Laparoscopic Versus Open Surgery for Colorectal Cancer

Inclusion Criteria: 1. Histologically proven colorectal carcinoma 2. Tumor located in the cecum, ascending colon, sigmoid colon, or rectosigmoid colon 3. T3 or deeper lesion without involvement of other organs 4. Without multiple lesion other than carcinoma in situ 5. Cancer classified as N0-2 and M0, according to the TNM classification system 6. Tumor size \< 8 cm 7. No bowel obstruction 8. Age 20 \< and \> 75 years 9. Sufficient organ function 10. No history of gastrointestinal surgery 11. No history of chemotherapy or radiotherapy 12. Provided written informed consent Exclusion Criteria: 1. Synchronous or metachronous (within 5 years) malignancy other than carcinoma in situ 2. Severe pulmonary emphysema, interstitial pneumonitis, or ischemic heart disease 3. Pregnant or lactating women 4. Severe mental disease 5. Continuous systemic steroid therapy