Sirolimus Eluting Stents in Complex Coronary Lesions (SCANDSTENT)

Inclusion Criteria: Stable, or unstable angina and/or objective signs of myocardial ischaemia Lesions should be de novo and located in native vessels with a diameter \> 2.25 mm. Complex lesions to be included should have at least one of the following characteristics: * Ostial in location (\< 5 mm from ostium) * Total occlusions with a length ≥ 15 mm * Bifurcational (side branch \> 1.75 mm in diameter) * Angulated (\> 45° within lesion) Exclusion Criteria: Patients: * Other severe disease with an expected survival \< 1 year * Other significant cardiac disease * Known allergy against paclitaxel, clopidogrel or stainless steel. * Myocardial infarction within 3 days of the index procedure * Linguistic difficulties needing an interpreter * Renal insufficiency (p-creatinine \> 200 micromol/l) * Gastrointestinal bleeding within 1 month * Childbearing potential or pregnancy * Participation in another study Lesions: * Unprotected left main disease * Restenosis * Lesions containing visible thrombus * Treatment with other modality than balloon or stent (ablation, brachytherapy, ultrasound) in connection with the index procedure * Diffuse coronary disease distal to the treated lesion * Heavily calcification * Lesion located in saphenous vein graft