Safety of SPD465 in Treating Adults With ADHD.

Inclusion Criteria: * Subject satisfied all entry criteria for the antecedent protocol (SPD465-301 or SPD465-303) and completed a minimum of 4 of the 7 weeks of double-blind treatment without experiencing any clinically significant adverse events. * Subject must be male or non-pregnant female who agrees to comply with using acceptable contraceptive methods. Exclusion Criteria: * Subject was terminated from antecedent protocol (SPD465-301 or SPD465-303) for non-compliance and/or experienced a serious adverse event or adverse event resulting in termination from the protocol. * Comorbid psychiatric diagnosis with significant symptoms such as Axis II disorders or severe Asix I disorders. * History of seizure, tic disorder, or a current diagnosis and/or family history of Tourette's Disorder. * Females who are pregnant of lactating.