Our previous data demonstrated that premature infants treated with inhaled nitric oxide at birth had improved neurodevelopmental outcomes at two years corrected age. We now wish to determine whether this benefit continues through school age.
Two questionnaires (truncated versions of previously validated surveys), one for parent and another for teacher, for which written consent was previously obtained are being sent to parents. The teacher questionnaires will be delivered via parents. A clinic visit will accompany age appropriate neurodevelopmental examination, administration of the Functional Independence Measure for Children (WeeFIM) survey, and hearing and visual screening exams (if appropriate).
Study Type
INTERVENTIONAL
Allocation
RANDOMIZED
Purpose
PREVENTION
Masking
QUADRUPLE
Enrollment
160
1 day of iNO at 10 ppm, then 5 ppm of iNO for days 2-7
No iNO given for days 1-7
The University of Chicago, Comer Children's Hospital,
Chicago, Illinois, United States
Examine school-readiness at school-age in premature infants treated with iNO or placebo in the first week of life
Time frame: 4-7 years of age (between 2005-2006)
Examine health status at early school-age
Time frame: 4-7 years of age (between 2005-2006)
This platform is for informational purposes only and does not constitute medical advice. Always consult a qualified healthcare professional.