The purpose of this study is to evaluate the efficacy, tolerability, and safety of the investigational drug, lumiracoxib as compared to celecoxib and placebo in subjects with hip osteoarthritis. Both lumiracoxib and celecoxib belong to the same class of drug (COX-2 selective nonsteroidal anti-inflammatory drugs \[NSAIDs\]).
Study Type
INTERVENTIONAL
Allocation
RANDOMIZED
Purpose
TREATMENT
Masking
DOUBLE
Enrollment
1,200
For US Site Information, contact Novartis Pharmaceuticals
East Hanover, New Jersey, United States
Various Sites
Multiple Cities, Canada
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Multiple Cities, Germany
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Multiple Cities, Italy
WOMAC 3.1 LK questionnaire after 13 weeks of treatment
Patient's global assessment of disease activity (VAS) after 13 weeks of treatment
Overall OA pain intensity (VAS)by visit
Physician's global assessment of disease activity (VAS) by visit
Response to treatment according to OARSI criteria by visit
Actual OA pain intensity at 12 hours post-dose by visit
Number of rescue tablets taken during the study
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Various Sites
Multiple Cities, United Kingdom