This clinical trial tries to use tissue fibrin glues (Tisseel) to treat various ocular surface diseases or surgeries, which includes pterygium surgery, corneal melting/perforation, Gunderson's flap, conjunctival laceration, and muscle/clinical/filtering surgery.
This clinical trial tries to use tissue fibrin glues (Tisseel) to treat various ocular surface diseases or surgeries. The inclusion criteria are: 1. ocular surface disease which may need amniotic membrane transplantation (corneal pro epithelization, pterygium surgery, etc) 2. infectious or noninfectious corneal ulcer with perforation less than 3 mm 3. conjunctival transplantation/suture 4. corneal surgeries which can be treated by conventional suture technique or application with cyanoacrylic acid tissue glues. Informed consents will be obtained from the patients before applications. After surgeries, topical steroids and antibiotics will be used, and therapeutic contact lens will be used. The patients will be followed up for at least three months.
Study Type
INTERVENTIONAL
Allocation
NON_RANDOMIZED
Purpose
TREATMENT
Masking
NONE
Enrollment
30
Apply several droplets within several seconds to several minutes
Wei-Li Chen
Dawan, Taiwan
cure of the diseases
Time frame: 1week, 2 weeks, 3 weeks, 4 weeks
integrity of the ocular surface
Time frame: 1week, 2 weeks, 3 weeks, 4 weeks
visual acuity
Time frame: 1week, 2 weeks, 3 weeks, 4 weeks
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