Effect And Safety Of Ziprasidone Compared To Other Atypical Antipsychotic Drug In Schizophrenic Patients

Pfizer's Upjohn has merged with Mylan to form Viatris Inc.290 enrolled

Overview

Evaluation of the antipsychotic efficacy and safety of ziprasidone versus olanzapine, risperidone or quetiapine in patients with schizophrenia, schizoaffective and schizophreniform disorders under naturalistic conditions of clinical practice

Study Type

INTERVENTIONAL

Allocation

RANDOMIZED

Purpose

TREATMENT

Masking

NONE

Enrollment

290

Conditions

Schizophrenia Schizoaffective Disorder Psychotic Disorders

Interventions

ziprasidone versus olanzapine , risperidone or quetiapineDRUG

Panss , CGI-C, UKU-SERS-PaBEHAVIORAL

Blood testsPROCEDURE

Eligibility

Sex: ALLMin age: 18 Years

Medical Language ↔ Plain English

Inclusion Criteria: * Inpatients or outpatients with schizophrenia, schizoaffective and schizophreniform disorders (DSM-IV). * Patients without adequate current treatment (i.e. intolerance to their current treatment or lack of efficacy of current treatment) based on clinical judgement of the investigator Exclusion Criteria: * A history of intolerance to ziprasidone, olanzapine, risperidone or quetiapine or any of its ingredients

Locations (43)

Outcomes

Primary Outcomes

PANSS (The Positive And Negative Syndrome Scale) in a 12 week period

Secondary Outcomes

CGI-C score (Clinical Global Impression of Change), UKU-SERS-Pa (Patient self rating version). Safety and tolerability: ECG, serum cholesterol, triglycerides, prolactin, glucose and body weight

Data from ClinicalTrials.gov

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Pfizer Investigational Site

Aalborg, Denmark

Pfizer Investigational Site

Arhus C, Denmark

Pfizer Investigational Site

Augustenborg, Denmark

Pfizer Investigational Site

Ballerup Municipality, Denmark

Pfizer Investigational Site

Brovst, Denmark

Pfizer Investigational Site

Copenhagen, Denmark

Pfizer Investigational Site

Dianalund, Denmark

Pfizer Investigational Site

Esbjerg, Denmark

Pfizer Investigational Site

Esbjerg N, Denmark

Pfizer Investigational Site

Glostrup Municipality, Denmark

...and 33 more locations