Endorectal Coil Magnetic Resonance Images (ERC-MRI)

University Health Network, Toronto20 enrolled

Overview

When we acquired MR images of the prostate gland using a coil (receiver antenna) inside the rectum, we can see areas with tumour in the prostate gland, and well as details of the anatomy. The coil inside the rectum changes the shape of the prostate gland. In order to use this images to help target radiation therapy to the tumour better, we need to deform the images to the original shape of the prostate gland without the coil. In this study, we will develop a way to deform the images accurately.

Study Type

INTERVENTIONAL

Allocation

RANDOMIZED

Purpose

PREVENTION

Masking

NONE

Enrollment

Conditions

Prostatic Neoplasms

Interventions

Endorectal Coil Magnetic Resonance ImagesPROCEDURE

Eligibility

Sex: MALEMin age: 18 Years

Medical Language ↔ Plain English

Inclusion Criteria: * adenocarcinoma of the prostate * patient undergoing dose escalated conformal EBRT * low or intermediate risk prognostic factors: PSA \< or equa to20, gleason score \<8, T \<T3, N category 0 or X, M category 0 or X * \> or equal to 18 years of age * ECOG performance status 0 or 1 Exclusion Criteria: * contraindications to MRI * bleeding diathesis and anti-coagulative therapy that cannot be temporarily ceased precluding insertion of fiducial markers * IFB or collagen vascular disease * previous colorectal surgery * previous pelvic RT

Locations (1)

Princess Margaret Hospital

Toronto, Ontario, Canada

Outcomes

Primary Outcomes

The primary aim of this study is to develop a prostate deformation model using the finite element method from anatomic MR images of the prostate gland acquired with and without ERC.

Data from ClinicalTrials.gov

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