Psychological Intervention for Relapse Prevention in First Episode Schizophrenia

University Hospital Tuebingen106 enrolled

Overview

The study is a randomized clinical trial investigating the efficacy of a comprehensive psychological intervention for the treatment of first episode schizophrenia

Patients suffering from their first episode of schizophrenic disorders are randomly allocated to either a short "information centered psychoeducation" (ICP) of 8 sessions or a "cognitive behavioral treatment" (CBT). CBT includes 8 sessions of psychoeducation, 8 sessions of computer based cognitive training, 8 sessions with relatives and 20 sessions of focusing on stress management, relapse prevention and coping with persistent symptoms. The primary endpoint is relapse at the one and two year follow up.

Study Type

INTERVENTIONAL

Allocation

RANDOMIZED

Purpose

TREATMENT

Masking

NONE

Enrollment

106

Conditions

Schizophrenic Disorders

Interventions

cognitive behavioural therapyBEHAVIORAL

psychoeducationBEHAVIORAL

Eligibility

Sex: ALLMin age: 18 YearsMax age: 55 Years

Medical Language ↔ Plain English

Inclusion Criteria: * diagnosis of schizophrenic disorder according to ICD 10: F20 * first episode * age between 18 and 55 * willingness to give informed consent also to a double blind pharmacological treatment study Exclusion Criteria: * residence outside of the catchment area * insufficient knowledge of the German language * substance abuse or addiction as primary clinical problem * serious physical illness * organic brain disease * pregnancy * contraindications to neuroleptic treatment

Locations (5)

Department of Psychiatry and Psychotherapy, University of Bonn

Bonn, Germany

Department of Psychiatry and Psychotherapy, University of Cologne

Cologne, Germany

Department of Psychiatry and Psychotherapy, University of Duesseldorf

Düsseldorf, Germany

Department of Psychiatry and Psychotheray, University of Muenchen

München, Germany

Outcomes

Primary Outcomes

relapse

Secondary Outcomes

quantitative measures of symptoms

social functioning

cognitive functioning

quality of life

Data from ClinicalTrials.gov

This platform is for informational purposes only and does not constitute medical advice. Always consult a qualified healthcare professional.