Topical Therapy for Prevention of Infections in Preterm Infants

Johns Hopkins Bloomberg School of Public Health600 enrolled

Overview

The purpose of this study is to determine how to best take care of the skin of preterm infants in order to prevent infections through the skin.

The skin of babies who are born too early is not mature, which means they are at risk for infections of the skin or in the body. Their skin also become very dry, leading to cracking and breakdown, and this may feel painful or uncomfortable for the infant.

Study Type

INTERVENTIONAL

Allocation

RANDOMIZED

Purpose

PREVENTION

Masking

NONE

Enrollment

600

Conditions

Skin Diseases

Interventions

AquaphorDRUG

Sunflower Seed OilDRUG

Eligibility

Sex: ALLMin age: 7 MonthsMax age: 8 MonthsHealthy volunteers:

Medical Language ↔ Plain English

Inclusion Criteria: * Preterm infants Exclusion Criteria: * Full-term infant

Locations (1)

Dhaka Shishu Hospital

Dhaka, Bangladesh

Outcomes

Primary Outcomes

Three weeks after application of the intervention, blood will be drawn from those enrolled in the control group.

Secondary Outcomes

Atleast four additional times over the first four weeks of the child's life, the skin will be studied by lightly rubbing the skin with a cotton swab to detect germs on the skin and observing and recording the condition of the baby's skin.

Data from ClinicalTrials.gov

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