To evaluate the effect of atorvastatin 80 mg, versus placebo, given for 12 months on carotid intima-media thickness in postmenopausal women with moderate hypercholesterolemia.
Study Type
INTERVENTIONAL
Allocation
RANDOMIZED
Purpose
TREATMENT
Masking
DOUBLE
Enrollment
400
Mean change in carotid IMT from baseline to month 12.
Mean change from baseline to month 12 of carotid internal diameter (ID)
wall cross sectional area (WCSA); carotid arterial mass (AM)
pulse pressure (PP); cross sectional distensibility and compliance (DC and CC)
pulse wave velocity (PWV); Lipid profile
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Afsnee GENT, Belgium
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Assenede, Belgium
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Brussels, Belgium
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Brussels, Belgium
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Brussels, Belgium
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Brussels, Belgium
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Brussels, Belgium
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Ertvelde, Belgium
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Ghent, Belgium
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Linkebeek, Belgium
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