Pulmonary Rehabilitation at Home Versus at the Gymnasium

Laval University252 enrolled

Overview

Short term efficacy of pulmonary rehabilitation for improving functional capacity and quality of life of chronic obstructive respiratory disease (COPD) patient is well known. However, there is an important gap between the scientific knowledge and the clinical use of pulmonary rehabilitation since a a very small number of patients benefit from this therapeutic intervention. We estimate that less than 1% of the 750 000 canadians suffering from COPD have access to a pulmonary rehabilitation program. We want to study the efficacy of a home-based rehabilitation program as a way to facilitate the access to rehabilitation.

This article on the main outcome is available. Maltais F, Bourbeau J, Shapiro S, Lacasse Y, Perrault H, Baltzan M, Hernandez P, Rouleau M, Julien M, Parenteau S, Paradis B, Levy RD, Camp P, Lecours R, Audet R, Hutton B, Penrod JR, Picard D, Bernard S. Effects of home-based pulmonary rehabilitation in patients with chronic obstructive pulmonary disease: a randomized trial. Ann Int Med 2008;149:869-878.

Study Type

INTERVENTIONAL

Allocation

RANDOMIZED

Purpose

PREVENTION

Masking

SINGLE

Enrollment

252

Conditions

COPD

Interventions

Pulmonary rehabilitation (teaching and exercise)BEHAVIORAL

After a 4-week education program, patients took part to home-based rehabilitation or outpatient hospital-based rehabilitation for 8 weeks. Patients were subsequently followed for 40 weeks to complete the one-year study.

Eligibility

Sex: ALLMin age: 40 YearsMax age: 95 Years

Medical Language ↔ Plain English

Inclusion Criteria: * Subject is able to ambulate. Defined as a 6MWD greater than 110 meters. * Subject is diagnosed with COPD. * 40 years-old and older * Currently or previously smoking with a smoking history of at least 10 pack-years. * Forced expiratory volume on one second (FEV1) after the use of a bronchodilator between 25 an 70% of the predicted value, and FEV1 to forced vital capacity ratio less than 70%. * No previous diagnosis of asthma, left heart congestive heart failure (either radiographic evidence of pulmonary congestion, echocardiographic or ventriculographic evidence of a reduced ventricular ejection fraction), terminal disease, dementia or uncontrolled psychiatric illness. * Never participated to a respiratory rehabilitation program and not staying or planning to stay in a long term care facility. * Subject understands and is able to read and write French or English. * MRC dyspnea scale of at least 2. Exclusion Criteria: * The need for supplemental oxygen at rest or during exercise will not be an exclusion criterion.

Locations (10)

St-Paul's Hospital

Vancouver, British Columbia, Canada

Halifax Infirmary

Halifax, Nova Scotia, Canada

CRMSBC/Centre Hospitalier Baie-des-Chaleurs

Bonaventure, Quebec, Canada

Jewish Rehabilitation Hospital

Outcomes

Primary Outcomes

The dyspnea of the chronic respiratory questionnaire (CRQ) at 12 months is the primary outcome variable.

Maltais F, Bourbeau J, Shapiro S, Lacasse Y, Perrault H, Baltzan M, Hernandez P, Rouleau M, Julien M, Parenteau S, Paradis B, Levy RD, Camp P, Lecours R, Audet R, Hutton B, Penrod JR, Picard D, Bernard S. Effects of home-based pulmonary rehabilitation in patients with chronic obstructive pulmonary disease: a randomized trial. Ann Int Med 2008;149:869-878.

Time frame: The data collection was terminated in January 2007 and publication was done December 2008

Secondary Outcomes

2-CRQ total score and specific domains, exercise tolerance (6MWD and submaximal exercise test) and ADL at 4 months.

Time frame: The data collection was terminated in January 2007.

3-Health service utilization (physician and emergency department visits, hospitalizations) over the 1-year study period.

Time frame: The data collection was terminated in January 2007.

4 Intervention cost.

Time frame: The data collection was terminated in January 2007.

Data from ClinicalTrials.gov

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