Study to assess the effects of tegaserod added to PPI therapy in the resolution of heartburn and regurgitation in patients with incomplete relief from PPIs .
Study Type
INTERVENTIONAL
Allocation
RANDOMIZED
Purpose
TREATMENT
Masking
DOUBLE
Enrollment
30
Consultants for Clinical Research of South Florida
Boynton Beach, Florida, United States
Miami Research Associates
Miami, Florida, United States
University Clinical Research
Pembroke Pines, Florida, United States
Department of Internal Medicine - Wake Forest University School of Medicine
Winston-Salem, North Carolina, United States
To determine the effect of 6 weeks of tegaserod in addition to proton pump inhibitors on heartburn and regurgitation (weekly assessment)
To evaluate the sensitivity of three global symptom assessments of GERD related to complaints (end of treatment compared to baseline)
To evaluate frequency, severity and bothersomeness of individual GERD symptoms (daily assessments)
To assess baseline characteristics that may predict a positive response to tegaserod add-on therapy in GERD patients
To assess patient satisfaction with treatment (end of treatment)
This platform is for informational purposes only and does not constitute medical advice. Always consult a qualified healthcare professional.
Consultants for Clinical Research
Cincinnati, Ohio, United States
Metropolitan Research
Fairfax, Virginia, United States
The Wisconsin Center for Advanced Research
Milwaukee, Wisconsin, United States