Atopic Dermatitis-Like Skin Disease in Pediatric Heart Transplant Patients

Phase 3TerminatedNCT00176956

Hordinsky, Maria K., MD30 enrolled

Overview

The skin disease found in pediatric heart transplant patients represents an atopic dermatitis-like rash that is refractory to systemic immunomodulation.

We want to determine whether pediatric heart transplant patients with an atopic dermatitis-like rash report a personal and/or family history of atopy (asthma, allergies and atopic dermatitis). In addition comparisons will be made between the presence of atopy between patients with and without the skin rash. Comparisons will be made of systemic immunosuppressive therapies between patients with and without the atopic dermatitis-like rash. Determination will be made as to whether histologic characterization of a skin biopsy specimen is consistent with AD. Thorough evaluations will be made of patients in the clinic with this rash and the presence of bacterial superinfection will be ruled out.

Study Type

INTERVENTIONAL

Enrollment

Conditions

Dermatitis

Interventions

Skin BiopsyPROCEDURE

Skin biopsy.

Eligibility

Sex: ALLMax age: 16 Years

Medical Language ↔ Plain English

Inclusion Criteria: * Patients must have had a heart transplant. * Patients must be less than 16 years of age. Exclusion Criteria: * Patients who have not had a heart transplant. * Patients who are greater than 16 years of age.

Locations (1)

University of Minnesota

Minneapolis, Minnesota, United States

Data from ClinicalTrials.gov

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