Effects of Comorbid Personality Disorder on the Treatment of Bipolar I Disorder

University of Pittsburgh13 enrolled

Overview

This study will examine the impact of comorbid personality disorder on the outcome of treatment among patients with bipolar I disorder.

The major aim of this proposal is to examine the impact of comorbid personality disorder on the outcome of treatment among patients with bipolar I disorder. The specific aims are to create a research and supervisory team and to identify potential moderators of treatment response and mediators of outcome over the course of treatment. Members of the team will meet weekly to begin a treatment development process for enhancing Interpersonal Social Rhythm Therapy (IPSRT) for these patients. Additional assessment measures will be utilized to examine the proposed mediators and moderators of treatment.

Study Type

INTERVENTIONAL

Allocation

NON_RANDOMIZED

Purpose

TREATMENT

Masking

NONE

Enrollment

Conditions

Bipolar I Disorder Borderline Personality Disorder

Interventions

Interpersonal Social Rhythm Therapy (IPSRT)BEHAVIORAL

Eligibility

Sex: ALLMin age: 18 YearsMax age: 60 Years

Medical Language ↔ Plain English

Inclusion Criteria: * Bipolar I Disorder with Comorbid Borderline Personality Disorder, currently manic or depressed Exclusion Criteria: * Unstable Medical illness

Locations (1)

Western Psychiatric Institute and Clinic

Pittsburgh, Pennsylvania, United States

Outcomes

Primary Outcomes

Hamilton Rating Scale for Depression (HRSD-25)

Secondary Outcomes

Raskin Severity of Depression and Mania Scales

Data from ClinicalTrials.gov

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