Measuring Alterations of DNA in Human Blood

University of Rochester24 enrolled

Overview

The purpose of this research is to evaluate an automated, laser-based technique for measuring DNA damge resulting from radiation. We want to use controlled exposure on cancer patients to help develop a measurement to test people who may have been accidentally exposed to radiation.

Study Type

OBSERVATIONAL

Enrollment

Conditions

Neoplasms

Eligibility

Sex: ALLMin age: 21 YearsMax age: 70 Years

Medical Language ↔ Plain English

Inclusion Criteria: * Male or female, age 21 to 70 years old. * Patient undergoing with anti-neoplastic agent(s) known to have genotoxic activity (e.g., cyclophosphamide, 5-FU, cisplatin, Ara-C. * X-irradiation may be considered, so long as a substantial fraction of red marrow is exposed (e.g., femur or chest/trunk region); * treatment could be ongoing therapy or initial therapy.

Locations (1)

University of Rochester

Rochester, New York, United States

Data from ClinicalTrials.gov

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