Study of Breath-holding as a Means to Reduce Tumor Motion From Breathing

University of Rochester10 enrolled

Overview

The purpose of this research study is to evaluate typical tumor motion caused by breathing using MRI and can help determine whether simple passive breathing and/or breath-holding could be used for the future treatment of similar lung and liver tumors using radiation therapy radiosurgery techniques.

Study Type

INTERVENTIONAL

Allocation

Purpose

TREATMENT

Masking

NONE

Enrollment

Conditions

Neoplasm, Metastatic

Interventions

MRI with breath-holdingPROCEDURE

Breath holding for diminished tumor motion.

Eligibility

Sex: ALLMin age: 18 Years

Medical Language ↔ Plain English

Inclusion Criteria: * The patient is enrolled on U8700 RSRB # A Phase II Study For Using Radiosurgery On Limited Metastases Of Breast Cancer or U9700 A Pilot Study For Using Radiosurgery On Limited Metastases. * ≥ 18 years of age * has given Informed consent Exclusion Criteria: -Contraindications for any MRI procedure

Locations (1)

University of Rochester Department of Radiation Oncology

Rochester, New York, United States

Outcomes

Primary Outcomes

Tumor Motion Related to Breathing as Determined From MRI Images

1. Determine the typical and maximal tumor 3D displacements over the respiratory cycle and how these values vary depending on the tumor location 2. Determine the reproducibility of target position over multiple breath-holds 3. Determine the variability across patients in respiratory-derived lesion motion and target position reproducibility over multiple breath-holds

Time frame: 20 - 30 seconds

Data from ClinicalTrials.gov

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