Evaluation of Immunoregulatory Cells in Hematopoietic Stem Cell Transplant

Vanderbilt University100 enrolled

Overview

The investigators' hypothesis is that the graft-versus-tumor effect can be enhanced while minimizing the complications of graft-versus-host disease.

The investigators' hypothesis is that the graft-versus-tumor effect can be enhanced while minimizing the complications of graft-versus-host disease (GVHD) by determining the qualitative and quantitative changes in T regulatory cells throughout the transplant process. Their understanding of this can lead to new treatment strategies and improved clinical therapeutic implications.

Study Type

OBSERVATIONAL

Enrollment

100

Conditions

Hematopoietic Stem Cell Transplantation Graft vs Host Disease

Eligibility

Sex: ALLMin age: 18 YearsMax age: 70 Years

Medical Language ↔ Plain English

Inclusion Criteria: * Patients 18-70 years old undergoing either autologous transplant or allogeneic transplant for various hematologic conditions Exclusion Criteria: * Patients \< 18 or \> 70 years old undergoing either autologous transplant or allogeneic transplant

Locations (1)

Vanderbilt University Medical Center

Nashville, Tennessee, United States

Data from ClinicalTrials.gov

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