The Effects of Protein Supplementation and Resistance Exercise in Hemodialysis Patients

Inclusion Criteria: * On hemodialysis for more than 3 months, on a thrice weekly hemodialysis program; * Adequately dialyzed (Kt/V \> 1.4). * Age \> 18 years old. * Properly functioning AV Graft Exclusion Criteria: * Patients unable to perform exercise due to cardiovascular disease, osteoarthritis, etc. * Pregnant women. * Severe unstable underlying disease besides commonly associated with ESRD. Cardiac patients that are stable will be included. * Patients hospitalized within the last month prior to the study. * Patients will not perform the MRI if contraindication as determined using the VUMC MRI Procedure Screening Form (attached) or prior claustrophobic reaction in an MRI scanner.