LMBA02 Protocol for Patients With a Burkitt Lymphoma

Inclusion Criteria: * Age : 18 years or older * Histologically or cytologically proven Burkitt lymphoma according to the WHO classification * WHO performance \< 3 * Informed consent Exclusion Criteria: * Known HIV positive infection * Positive serology for HCV and HBV (except after vaccination) * Patients previously treated for lymphoma * cardiac disease that contradict anthracycline chemotherapy * Psychological or psychiatric condition who contradict steroids therapy * Patients with serious renal failure unrelated to the lymphoma (serum creatinin level higher than 150 mmole/L) * Cirrhosis or severe hepatic failure unrelated to the lymphoma * Previous malignant disease except basal cell skin carcinoma or in situ uterine cervix carcinoma * Any psychological, familial, sociological or geographical condition potentially hampering compliance with the study protocol and follow-up schedule * Primary organ transplant or other immunosuppressive conditions Pregnancy