Effect of Increased Oxygenation in the Air During Endurance Training in Stable Angina Pectoris Patients

Norwegian University of Science and Technology25 enrolled

Overview

The study investigates whether endurance training breathing 100% oxygen gives a additional improvement of maximal oxygen uptake in stable Angina Pectoris patients, compared to training without extra oxygen supplementation. In addition work economy, stroke volume and cardiac perfusion is measured. The hypothesis of the study is that increased oxygenation of the air increases performance, stroke volume, work economy and cardiac perfusion.

Study Type

INTERVENTIONAL

Allocation

NON_RANDOMIZED

Purpose

TREATMENT

Masking

NONE

Enrollment

Conditions

Angina Pectoris

Interventions

Hypoxic interval trainingBEHAVIORAL

4 x 4 minutes interval training in hypoxic air, 3 times per week at 90-95% HR max

Normoxic interval trainingBEHAVIORAL

4 x 4 minutes normoxic interval training, 3 times per week at 90-95% HR max

Eligibility

Sex: ALLMin age: 18 YearsMax age: 75 Years

Medical Language ↔ Plain English

Inclusion Criteria: * stable angina pectoris age 18-75 Exclusion Criteria: * unstable angina pectoris * Limitations to exercise other than coronary artery disease * Participants in other study interventions

Locations (1)

Norwegian University of Science and Technology

Trondheim, Norway

Outcomes

Primary Outcomes

maximal oxygen uptake

Time frame: Baseline and post training

Secondary Outcomes

Cardiac perfusion

Time frame: Baseline and post training

work economy

Time frame: Baseline and post training

cardiac output

Time frame: baseline and post training

Data from ClinicalTrials.gov

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