Comparison of Biphasic Insulin Aspart 70/30, 50/50, and 30/70 in Subjects With Type 2 Diabetes

Novo Nordisk A/S603 enrolled

Overview

This trial is conducted in Europe. This trial aims for a comparison of the effect on glycemic control in subjects with type 2 diabetes of three different premixed insulin analogues given in combination with an oral anti-diabetic drug.

Study Type

INTERVENTIONAL

Allocation

RANDOMIZED

Purpose

TREATMENT

Masking

NONE

Enrollment

603

Conditions

Diabetes Diabetes Mellitus, Type 2

Interventions

biphasic insulin aspartDRUG

metforminDRUG

Eligibility

Sex: ALLMin age: 18 Years

Medical Language ↔ Plain English

Inclusion Criteria: * Type 2 diabetes * Currently treated with insulin * Currently treated with Metformin * HbA1c: 7.5-12.0% Exclusion Criteria: * Body Mass Index (BMI) \< 25.0 or \> 40.0 kg/m2 * Metformin contraindications according to local practice * TZDs within 6 months prior to randomisation

Locations (108)

Outcomes

Primary Outcomes

HbA1c

Time frame: after 36 weeks

Secondary Outcomes

8-point plasma glucose profiles

Safety variables

Other glycemic variables

Data from ClinicalTrials.gov

This platform is for informational purposes only and does not constitute medical advice. Always consult a qualified healthcare professional.