The aim of the study is to test \[90\]Y-ibritumomab tiuxetan, a radioactive antibody, in patients with stage III or IV follicular lymphoma whose disease is in partial or complete remission after first line chemotherapy. The radioactive antibody will be compared with no further treatment to see which is better in the long term after standard lymphoma treatment.
The study has previously been posted by Schering AG, Germany. Schering AG, Germany has been renamed to Bayer Schering Pharma AG, Germany. Bayer Schering Pharma AG, Germany is the sponsor of the trial.
Study Type
INTERVENTIONAL
Allocation
RANDOMIZED
Purpose
TREATMENT
Masking
NONE
Enrollment
414
treatment with 90 Yttrium-labeled anti CD 20 antibody
no treatment
Progression free survival
Time frame: End of study
Clinical and molecular response rates
Time frame: End of study
Overall survival
Time frame: End of study
Quality of Life
Time frame: End of study
Adverse events / Toxicity Grading
Time frame: Continous
Clinical laboratory results
Time frame: 3 monthly
Vital signs / physical examination
Time frame: 3 monthly
ECG
Time frame: End of study
Co-medication
Time frame: Continous
This platform is for informational purposes only and does not constitute medical advice. Always consult a qualified healthcare professional.
Unnamed facility
Antwerp, Belgium
Unnamed facility
Bruges, Belgium
Unnamed facility
Brussels, Belgium
Unnamed facility
Ghent, Belgium
Unnamed facility
Leuven, Belgium
Unnamed facility
Yvoir, Belgium
Unnamed facility
Edmonton, Alberta, Canada
Unnamed facility
Vancouver, British Columbia, Canada
Unnamed facility
Hamilton, Ontario, Canada
Unnamed facility
Ottawa, Ontario, Canada
...and 85 more locations