For twin pregnancies at 32-38 weeks gestation, where twin A is head down, does a policy of planned caesarean section (CS) lower the likelihood of death or serious illness, during the first 28 days after birth, compared to a plan for vaginal birth (VB)?
For twin pregnancies of 32-38 weeks gestation, where twin A is presenting cephalic, does a policy of planned CS decrease the likelihood of perinatal or neonatal mortality or serious neonatal morbidity, during the first 28 days after birth, compared to a policy of planned VB?
Study Type
INTERVENTIONAL
Allocation
RANDOMIZED
Purpose
TREATMENT
Masking
NONE
Enrollment
2,804
CS or VB
Data Coordinating Centre/SHSC
Toronto, Ontario, Canada
Perinatal/Neonatal Mortality and/or Serious Neonatal Morbidity
The primary outcome was a composite of fetal or neonatal mortality or serious neonatal morbidity.
Time frame: until 28 days after delivery
Neonatal Morbidity
Neonatal morbidity, excluding death of either twin
Time frame: until 28 days after delivery
Death or Poor Neurodevelopmental Outcome of the Children at 2 Years of Age (Corrected for Gestational Age at Birth)
Neurodevelopmental outcome will be assessed by the Ages and Stages Questionnaire (ASQ). The ASQ is a parent/parental caregiver-administered structured questionnaire that includes questions on 5 domains of development: communication, gross motor skills, fine motor skills, problem-solving skills, and personal-social skills. If the score for any 1 of the 5 domains is below the specific cutoff for the domain, the ASQ was considered abnormal.
Time frame: 2 years
Problematic Urinary or Faecal/Flatal Incontinence of Mothers at 2 Years Postpartum
The occurrence of problematic urinary, faecal/flatal incontinence at 2 years following the birth will be determined by structured questionnaire
Time frame: 2 years postpartum
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