A Study to Assess Efficacy, Safety and Pharmacokinetics of a Tacrolimus New Oral Formulation (MR4) in BMT Recipients

Inclusion Criteria: * Bone marrow transplantation patients aged 20-54 except for transplanted from genetically HLA matched sibling donor. * The patient had been fully informed. Exclusion Criteria: * The patient had severe impaired hepatic function. * The patient had impaired renal function. * The patient had existing complication of severe cardiac dysfunction. * The patient had severe impaired pulmonary function.