Factor V Leiden Mutation and Implantation Failure

N/ACompletedNCT00194350

University of Pennsylvania399 enrolled

Overview

The purpose of this study is to determine whether inherited thrombophilias (tendency toward blood clotting) increase the risk of failure of the embryo to implant in IVF. The specific condition to be studied is the presence or absence of the Leiden mutation of the Factor V gene.

Study Type

OBSERVATIONAL

Enrollment

399

Conditions

Infertility

Interventions

Test for Factor V Leiden gene mutationPROCEDURE

Eligibility

Sex: FEMALEMin age: 18 Years

Medical Language ↔ Plain English

Inclusion Criteria: * Women undergoing in-vitro fertilization with successful ovarian hyperstimulation, oocyte retrieval, and fertilization * Transfer of at least 2 fresh embryos of Grade 2 (preembryo with blastomeres of equal size and \<=10% cytoplasmic fragmentation) or better Exclusion Criteria: * Infertility due to uterine anatomic defect * Current use of anticoagulant medication, such as heparin or aspirin * Known presence of any other condition associated with increased risk of thrombosis

Locations (1)

University of Pennsylvania Reproductive Research Unit

Philadelphia, Pennsylvania, United States

Data from ClinicalTrials.gov

This platform is for informational purposes only and does not constitute medical advice. Always consult a qualified healthcare professional.