Study Evaluating Sirolimus in Kidney Transplant Recipients in India

Inclusion Criteria: * Patients in End Stage Renal Disease who are above 13 years of age and weigh more than 40 kilograms. * Patients scheduled to receive a kidney from a cadaveric donor, from a living unrelated donor or from a living related donor. Exclusion Criteria: * Evidence of major infections at the time of sirolimus administration * Use of any investigational drug or treatment up to 4 weeks prior to enrolling in the study and during the treatment phase. * Females who are pregnant, breast feeding or in reproductive age group and not using a medically acceptable form of contraception