Study Evaluating DVS-233 SR for Treatment of Vasomotor Symptoms Associated With Menopause

Inclusion Criteria: * Postmenopausal women of age 40 to 65 seeking treatment for hot flashes with last natural menstrual period (LNMP) completed at least 12 months prior to screening. * Minimum of 7 moderate to severe hot flashes per day or 50 per week recorded for 7 consecutive days * Body Mass Index less than or equal to 34 kg/m2 using the nomograph for BMI. Exclusion Criteria: * History, presence, or suspicion of estrogen-dependent neoplasia; Malignancy, or treatment for malignancy, within the previous 2 years. * Active or recent arterial thromboembolic disease; History of venous thromboembolism * History of cerebrovascular accident, stroke, or transient ischemic attack - * Presence of major depressive disorder, bipolar disorder, psychotic disorder, or generalized anxiety disorder requiring therapy * Persistent elevated blood pressure