Study About Effectiveness of Silver-Containing Textiles for Treatment of Acute Neurodermatitis

Phase 3CompletedNCT00196430

University Medicine Greifswald32 enrolled

Overview

The purpose of this study is to investigate whether the treatment of acute neurodermitis with silver-contained textiles is equivalent or more effective to the conservative exogenous treatment with a corticosteroid. Secondary aim is to define skin comfortability of the textiles.

Study Type

INTERVENTIONAL

Allocation

RANDOMIZED

Purpose

TREATMENT

Masking

SINGLE

Enrollment

Conditions

Neurodermatitis

Interventions

silver-contained textilesDEVICE

corticosteroidDRUG

Eligibility

Sex: ALLMin age: 2 YearsMax age: 70 Years

Medical Language ↔ Plain English

Inclusion Criteria: * Clinical diagnosis of acute Neurodermitis * Age: 2-70 years * Patients are mobile * Patient's information and willingness to participate Exclusion Criteria: * Acute viral infection (herpes zoster, eczema herpeticum) * Acute staphylodermas * Other skin-diseases affecting outcomes of intervention (e.g. psoriasis) * Current UV-Treatment * Current other immunosuppressive or immunomodulated Therapy * Current antimicrobial Therapy (e.g. antibiotics) * Severe general diseases (e.g. melanoma, renal insufficiency, autoimmune diseases) * Pregnancy * Fertile females without effective contraception

Locations (1)

Clinic and Polyclinic of Dermatology, Ernst-Moritz-Arndt-University of Greifswald

Greifswald, Fleischmannstr. 42-44, Germany

Outcomes

Primary Outcomes

SCORAD at days -3,0,7,14,28,56 for every group

Secondary Outcomes

Influence of silver containing textiles in reducing bacterial skin colonization (especially Staph. aureus)

Consumption of corticosteroids at days 0-28

Consumption of corticosteroids at days 28-56

Pruritus under textiles

Evaluation of quality of life

Data from ClinicalTrials.gov

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