Assessment of the therapeutic effect of deep brain stimulation of the subthalamic nucleus compared with drug treatment alone in patients with advanced Parkinson's disease.
Patients are randomized either to medical treatment or subthalamic stimulation. The observation period was 6 months. The primary outcome criterium: PDQ-39 and UPDRS III.
Study Type
INTERVENTIONAL
Allocation
RANDOMIZED
Purpose
TREATMENT
Masking
NONE
Enrollment
156
Neurologische Klinik der Charité, Augustenburgerplatz 1
Berlin, Germany
Neurologische Klinik der Universität, Gleuelerstr. 50
Cologne, Germany
Neurologische Klinik der Universität, Moorenstr. 5
Düsseldorf, Germany
Neurologische Klinik der Universität, Neuenheimerfeld 400
Heidelberg, Germany
Quality of life
Motor Score in the OFF (UPDRS III)
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Department of Neurology, Schittenhelmstr. 10
Kiel, Germany
Neurologische Klinik der Universität
München, Germany