Treatment of Elderly Patients (>65 Years) With Acute Lymphoblastic Leukemia

Inclusion Criteria: * diagnosis of acute lymphoblastic leukemia (pro-B,common,pre-B,pre-T,Thy-,mature T, B-ALL) * age \> 65 years * written informed consent * Karnofsky \> 50% (if not mainly caused by leukemia) * laboratory at diagnosis or after supportive pre-treatment Creatinine \< 2 mg/dl Uric Acid \< 8 mg/dl Bilirubin \< 1.5 mg/dl ALA, ASA,AP \< 2.5 x ULN Exclusion Criteria: * severe second diseases (e.g. renal failure, cardiomyopathy etc., not caused by leukemia) that exclude treatment according to the protocol * severe psychiatric illness or other circumstances which may compromise cooperation * active second neoplasia * clinical signs of life threatening infections or bleeding, uncontrollable prior to chemotherapy