The follow up of colorectal cancer after curative surgery has to find loco-regional relapses or synchronous metastases, and to detect adenomas and new cancer on the rest of the colon. The increase of survival after relapse of the colorectal cancer depends on the possibility of curative action or after chemotherapy response. This is a Phase III open-labeled, multicenter, multidisciplinary, randomised study, comparing 2 arms of 188 patients (i.e. 376 total patients). Study Period (date of first inclusion/last inclusion): 3 years. Follow Up: 3 years. The primary objective is the evaluation of PET performance in the earlier relapse detection of the colorectal cancer relapse in comparison with conventional control (including carcinoembryonic \[CEA\] levels and other classic radiological exams).
Study Type
INTERVENTIONAL
Allocation
RANDOMIZED
Purpose
DIAGNOSTIC
Masking
NONE
Enrollment
376
Cancérologie et Hépato-Gastro-Entérologie
Bordeaux, France
Institut François Baclesse
Caen, France
Médecine Nucléaire
Limoges, France
Oncologie Médicale
Limoges, France
Oncologie Digestive
Marseille, France
Time to colorectal cancer relapse
Evaluation of overall survival in the two groups
Time frame: after curative resection of colorectal cancer stage II or III
Evaluation of the rate of curative surgery
Time frame: after relapse
Comparison of the medical cost in the two detection strategies
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