Hemodynamic Measurements During Cesarean Section With Spinal Anesthesia

Phase 4CompletedNCT00199784

Oslo University Hospital80 enrolled

Overview

The purpose of this study is to determine the effect of low dose versus standard dose spinal anesthesia with and without intravenous phenylephrine-infusion on blood pressure, cardiac output and systemic vascular resistance.

Hypotension during cesarean section with spinal anesthesia is common. We compare low dose versus standard dose spinal anesthesia with and without intravenous phenylephrine-infusion.

Study Type

INTERVENTIONAL

Allocation

RANDOMIZED

Purpose

PREVENTION

Masking

DOUBLE

Enrollment

Conditions

Healthy

Interventions

PhenylephrineDRUG

Eligibility

Sex: FEMALEMin age: 18 YearsMax age: 50 YearsHealthy volunteers:

Medical Language ↔ Plain English

Inclusion Criteria: * Healthy pregnant women for elective cesarean section Exclusion Criteria * Shorter than 160 or taller than 180 cm * Pre-pregnant body mass index (BMI) over 32

Locations (1)

Rikshospitalet-Radiumhospitalet HF

Oslo, Oslo, Norway

Outcomes

Primary Outcomes

Differences in cardiac output

Blood pressure

Systemic vascular resistance

Secondary Outcomes

Nausea

Fatigue

Cardiovascular instability due to overdosing spinal anesthesia for cesarean section (CS)

Data from ClinicalTrials.gov

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