An endometrial biopsy involves a thin tube being passed through the cervix (opening of the uterus) to obtain a sample of the lining of the uterus. Sometimes there may be discomfort with this procedure especially if the cervix is not dilated or opened. Previous research has suggested that taking a drug called misoprostol may help the cervix to start to dilate or open. This study will see if misoprostol will help open the cervix for an endometrial biopsy, to lessen the discomfort and make the biopsy easier to perform.
Study Type
INTERVENTIONAL
Allocation
RANDOMIZED
Purpose
TREATMENT
Masking
TRIPLE
Enrollment
72
misoprostol 400mcg 12 hrs prior to procedure
Vitamin B6 50 mg orally 12 hrs prior to procedure
Women's Health Centre, Eastern Health
St. John's, Newfoundland and Labrador, Canada
Obstetrics and Gynecology Associates
Dartmouth, Nova Scotia, Canada
pain/discomfort of endometrial biopsy
Time frame: during procedure
ease of performing biopsy
Time frame: during procedure
success of obtaining biopsy
Time frame: during procedure
potential side effects
Time frame: time study drug taken until procedure
This platform is for informational purposes only and does not constitute medical advice. Always consult a qualified healthcare professional.