The purpose of this study is to determine the potential safety and effectiveness of rebamipide eye drops, an investigational eye drop being developed for the treatment of keratoconjunctivitis sicca (dry eye).
There is a need for effective therapy for dry eye that treats the underlying cause of the syndrome. The goal of this study is to assess the impact of rebamipide on dry eye symptoms.
Study Type
INTERVENTIONAL
Allocation
RANDOMIZED
Purpose
TREATMENT
Masking
TRIPLE
Enrollment
762
ophthalmic suspension
ophthalmic suspension
Rebamipide-matching placebo ophthalmic suspension
fluorescein corneal staining (FCS) total score at week 12 and the average primary ocular discomfort (POD) severity score at week 12
Time frame: 12 week
fluorescein corneal staining (FCS) total score at week 26 and the average primary ocular discomfort (POD) severity score at week 26
Time frame: 26 week
This platform is for informational purposes only and does not constitute medical advice. Always consult a qualified healthcare professional.
Harold Helms, MD
Birmingham, Alabama, United States
Michael Bernstein, MD
Birmingham, Alabama, United States
I Care! Eye Care!
Flagstaff, Arizona, United States
Harvey and Bernice Jones Eye Institute
Little Rock, Arkansas, United States
United Medical Research Institute
Inglewood, California, United States
Benchmark Research
San Francisco, California, United States
Southern California Clinical Research, Inc.
San Marino, California, United States
Colorado Eye Associates, PC
Colorado Springs, Colorado, United States
Danbury Eye Physicians and Surgeons, P.C.
Danbury, Connecticut, United States
Florida Ophthalmic Institute
Gainesville, Florida, United States
...and 50 more locations