Efficacy and Safety of Ivabradine on Top of Atenolol in Stable Angina Pectoris

Phase 3CompletedNCT00202566

Institut de Recherches Internationales Servier750 enrolled

Overview

To test whether ivabradine when given in combination with atenolol is able to improve the exercise tolerance of patients with stable angina pectoris

Study Type

INTERVENTIONAL

Allocation

RANDOMIZED

Masking

DOUBLE

Enrollment

750

Conditions

Angina Pectoris

Interventions

IvabradineDRUG

Eligibility

Sex: ALLMin age: 18 YearsMax age: 75 Years

Medical Language ↔ Plain English

Inclusion Criteria: * Chronic stable angina pectoris * Documented coronary artery disease * Previous treatment with atenolol or other beta-blocker agent * Exercise tolerance test positivity and stability Exclusion Criteria: * Heart rate \< 60 bpm * Congestive heart failure

Locations (1)

Montreal Heart Institute

Montreal, Quebec, Canada

Outcomes

Primary Outcomes

Improvement between baseline and end of treatment of the treadmill exercise tolerance test

Secondary Outcomes

Rate pressure product

Clinical evaluation

Data from ClinicalTrials.gov

This platform is for informational purposes only and does not constitute medical advice. Always consult a qualified healthcare professional.