Safety and Efficacy of SPD465 in Adults With ADHD

Inclusion Criteria: * Primary diagnosis of ADHD using DSM-IV-TR criteria (at least 6 of the 9 subtype criteria met) * Baseline ADHD-RS-IV score =\>24 * IQ score of =\> 80 (using Kaufman Brief Intelligence Test) Exclusion Criteria: * BMI \< 18.5 or \> 30 kg/m2 * Diagnosis of Post Traumatic Stress Disorder, psychosis, bipolar illness, severe obsessive compulsive disorder, severe depressive or severe anxiety disorder * History of seizure disorder or a lifetime history of any seizures (other than infantile febrile seizures), any tic disorder, or a current diagnosis and/or family history of Tourette's Disorder * History of uncontrolled hypertension or currently hypertensive * Subjects who have taken atomoxetine (STRATTERA) within 30 days prior to screening * Current (or history within the last 12 months) of drug dependence or substance abuse disorder according to DSM-IV-TR criteria (excluding nicotine) * Female subject is pregnant or lactating, less than 3 months post partum